Pinealon
PH-PIN-001
Specifications
Description
Pinealon is a tripeptide (Glu-Asp-Arg) that regulates gene expression in brain cells. This synthetic peptide is based on natural pineal gland peptides and has been studied for cognitive and neuroprotective effects.
Mechanism of Action
Pinealon penetrates cell membranes and interacts with DNA, influencing gene expression patterns associated with neuronal function. The peptide protects neurons from prenatal hyperhomocysteinemia, improving cognitive function and resistance to oxidative stress (Arutjunyan et al., 2012). Pinealon has the most pronounced antihypoxic properties among short regulatory peptides, increasing neuronal resistance to hypoxic stress (Khavinson et al., 2008).
Research Applications
- Cognitive function research (Arutjunyan et al., 2012)
- Neuroprotection studies (Khavinson et al., 2008)
- Aging and geroprotection
- Gene expression regulation
- Pineal gland peptide research
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 418.4 Da
- Sequence: Glu-Asp-Arg
- Form: Lyophilized powder
- Storage: -20°C
References
- Arutjunyan A, et al. "Pinealon protects the rat offspring from prenatal hyperhomocysteinemia." Int J Clin Exp Med. 2012. PMID: 22567179
- Khavinson VKh, et al. "Investigation of antihypoxic properties of short peptides." Eksp Klin Farmakol. 2008. PMID: 18546825
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
Pinealon is a synthetic peptide compound used in laboratory research settings. Researchers studying cognitive function and neuroprotection use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for Pinealon — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is Pinealon?
Each lot of Pinealon is verified to ≥99% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does Pinealon include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for Pinealon documents its purity and identity and is available on our COA page.
How should Pinealon be stored?
Pinealon is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is Pinealon shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can Pinealon be used on humans or animals?
No. Pinealon is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
