Melanotan II
PH-MT2-001
Specifications
Description
Melanotan II is a synthetic analog of alpha-melanocyte stimulating hormone (α-MSH) that activates melanocortin receptors MC1R through MC5R. This cyclic heptapeptide was developed for tanning and sexual dysfunction research.
Mechanism of Action
Melanotan II binds to melanocortin receptors, stimulating melanogenesis through MC1R and affecting appetite and sexual function via MC3R and MC4R. Studies show effects on thermogenic capacity (PMID: 33332767) and appetitive behavior (PMID: 36155088).
Research Applications
- Melanocortin receptor pharmacology (PMID: 33332767)
- Appetite regulation (PMID: 36155088)
- Pigmentation studies
- Sexual function research
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 1024.18 Da
- Form: Lyophilized powder
- Storage: -20°C, protected from light
References
- Melanotan II thermogenic study. 2020. PMID: 33332767
- Melanotan II appetite study. 2022. PMID: 36155088
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
Melanotan II is a synthetic peptide compound used in laboratory research settings. Researchers studying melanocortin receptor system research use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for Melanotan II — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is Melanotan II?
Each lot of Melanotan II is verified to ≥99% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does Melanotan II include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for Melanotan II documents its purity and identity and is available on our COA page.
How should Melanotan II be stored?
Melanotan II is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is Melanotan II shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can Melanotan II be used on humans or animals?
No. Melanotan II is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.


