LL-37
PH-LL37-001
Specifications
Description
LL-37 is the only human cathelicidin antimicrobial peptide, a 37-amino acid sequence with broad-spectrum antimicrobial and immunomodulatory properties.
Mechanism of Action
LL-37 disrupts microbial membranes and modulates immune responses. Research demonstrates antimicrobial activity in platelets (PMID: 36769137) and roles in oral health (PMID: 41544412).
Research Applications
- Antimicrobial peptide research (PMID: 41544412)
- Innate immunity studies (PMID: 36769137)
- Wound healing research
- Immunomodulation studies
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 4493 Da
- Form: Lyophilized powder
- Storage: -20°C
References
- LL-37 oral health review. 2025. PMID: 41544412
- LL-37 platelet antimicrobial activity. 2023. PMID: 36769137
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
LL-37 is a synthetic peptide compound used in laboratory research settings. Researchers studying antimicrobial peptide activity use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for LL-37 — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is LL-37?
Each lot of LL-37 is verified to ≥99% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does LL-37 include a Certificate of Analysis?
Yes. A batch-specific Certificate of Analysis for LL-37 documents its purity and identity and is available on our COA page.
How should LL-37 be stored?
LL-37 is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is LL-37 shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can LL-37 be used on humans or animals?
No. LL-37 is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
