Follistatin-344
PH-FST344
Specifications
Description
Follistatin-344 is a single-chain glycoprotein that binds and neutralizes members of the TGF-β superfamily, particularly myostatin and activin. This naturally occurring protein is a key regulator of muscle growth.
Mechanism of Action
Follistatin-344 binds myostatin with high affinity, preventing it from activating its receptor and suppressing muscle growth. Research shows roles in muscle hypertrophy and reproductive signaling (Esposito et al., 2022). Studies in IBD show diagnostic potential (Skrzypczak et al., 2021).
Research Applications
- Myostatin inhibition studies (Esposito et al., 2022)
- Muscle growth research (Skrzypczak et al., 2021)
- Muscular dystrophy models
- Biomarker research
Product Specifications
- Purity: ≥98% (HPLC verified)
- Molecular Weight: ~38 kDa
- Form: Lyophilized powder
- Storage: -20°C
References
- Esposito P, et al. J Transl Med. 2022. PMID: 35152972
- Skrzypczak D, et al. J Clin Med. 2021. PMID: 34680417
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
Follistatin-344 is a synthetic peptide compound used in laboratory research settings. Researchers studying growth hormone releasing hormone pathways use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
Frequently Asked Questions
What purity is Follistatin-344?
Each lot of Follistatin-344 is verified to ≥98% by HPLC and confirmed by mass spectrometry. Results are documented in a batch-specific Certificate of Analysis.
Does Follistatin-344 include a Certificate of Analysis?
Yes. Every order includes batch-specific analytical documentation — a Certificate of Analysis covering purity and identity.
How should Follistatin-344 be stored?
Follistatin-344 is supplied as a lyophilized powder. For short-term storage keep it refrigerated; for long-term storage keep it frozen, away from light and moisture.
How is Follistatin-344 shipped?
Orders ship at a $15 flat rate, free on orders over $199, in discreet, insulated packaging. Domestic delivery typically takes 1–3 business days.
Can Follistatin-344 be used on humans or animals?
No. Follistatin-344 is supplied strictly for in-vitro laboratory research. It is not for human or veterinary use, consumption, or diagnostic or clinical applications.
